Viju Vijayan 1.5 year old female rottweiler dog, wt 40kg, limb edema since last 2 months.unilateral purulent occular discharge. vaccination and deworming regular. food intake normal.
wet film examination microfilaria ++. blood smear- no blood parasites detected.
Tx ivermectin, lasix.
no improvement even aftr 2 weeks of treatment.
Tx- ...OTC, magsulph glycerine.
x ray- no bone pathologies,
enlargement of popleteal lymph nodes
hemogram-
rbc-2.9
wbc-24500/cmm
platelet-299000/cmm
n-80%, L-20%,Hb- 8.7, PCV- 28%
today again came no improvement.
could the case be Pythiosis coz earlier we got a similar case that responded to itraconazole treatment.
began itroconazole tx
Saurabh Saxena
cardiac auscultation and ecg??exercise tolerance etc..
20 February at 11:02
Swarupmay Majumdar
interesting case,please keep updating doc.
use some other antibiotic also. why not try DEC? avl in tablets for phylariasis.
I think Lymphnode enlargements are mostly due to localizeed reasons.
use some other antibiotic also. why not try DEC? avl in tablets for phylariasis.
I think Lymphnode enlargements are mostly due to localizeed reasons.
20 February at 14:41 ·
Amardeep Singh
SM i am uploading the pic of a similar case
20 February at 16:21
Darsha Mapatuna
do the lab test to discharge . check the heart function also.
give 4 generation of cephlalosporins antibiotics and apply MgSO4 topically
give 4 generation of cephlalosporins antibiotics and apply MgSO4 topically
20 February at 17:11
Swarupmay Majumdar
AD sir, please post it on SAVIN, many of the members who are not in your friends list may not be able to see them. Thanks.
20 February at 17:14 ·
Muthuswamy Anantharaman
y the thinking of Pythiosis when the wet film is positive microfilaria??
20 February at 18:39
Viju Vijayan
after ivermectin Tx microfilaria was -ve, when done wet film examination one week after
20 February at 18:54
Gautam Unny
what about DEC
22 February at 17:28
Padma Yadlapalli
Sorry for my ignorance but what is DEC
was the edema localized to only that limb;
Also he seems so anemic with that RBC coount any other pathology noted on the smear; were you able to get a chemistry or profile done; what was his albumin or TP if so
was the edema localized to only that limb;
Also he seems so anemic with that RBC coount any other pathology noted on the smear; were you able to get a chemistry or profile done; what was his albumin or TP if so
25 February at 02:29
Swarupmay Majumdar
DEC= diethylcarbamazine.
25 February at 08:56 ·
Swarupmay Majumdar
please update on his condition.
25 February at 18:28 ·
Padma Yadlapalli
oh thank you
25 February at 19:38
Viju Vijayan
@padma yes the edems was localised on that limb.
@swarupmay doc, the draining tracts on the edematous leg disappeared after itraconazole treatment, still continuing with it, the disappearence of draining tracts , i thik is supporting pythiosis as the culprit
@swarupmay doc, the draining tracts on the edematous leg disappeared after itraconazole treatment, still continuing with it, the disappearence of draining tracts , i thik is supporting pythiosis as the culprit
26 February at 00:22
Swarupmay Majumdar
I have no ideas of this term called "pythiosis", please can u give me some informations or links on it.
26 February at 14:40 ·
Gautam Unny
viju, why did u choose itraconazole over fluconazole or ketoconazole, itra is very costly for long duration treatment which any fungal ailment normally is?? please tell me why u preferred itra? did you choose it because of the more convinient dosage regime of 5mg/kg/day?/
26 February at 19:12
26 February at 22:56
Joseph Cyrus
any history of colitis, pythiosis is also associated with LI signs? U should have done a culture as systemic mycosis cases are not so reported in INdia and it would have been reslly helpful. What could have been the source of the infection? Zoonoses?
28 February at 09:59
Viju Vijayan
not sure abt the reason. pythiosis occurs in 2 forms the GI form as well as the cutaneous form
. i think it might be the cutaneous form, as, so far the animal is responding to the Tx
. i think it might be the cutaneous form, as, so far the animal is responding to the Tx
28 February at 12:12
Viju Vijayan
the animal responded well to the tx.
the edema subsided. but unfortunately died yesterday, respiratory trouble. i thik it would have been the consequence of the systemic form that might have been present. any comments or suggestions
the edema subsided. but unfortunately died yesterday, respiratory trouble. i thik it would have been the consequence of the systemic form that might have been present. any comments or suggestions
11 March at 18:06
Swarupmay Majumdar
the dog had low Hb, not sure abt Liver profile,kidney profile. did it die becoz of organ fails.
11 March at 18:14 ·
Viju Vijayan
not sure. the owner didnt turn up. might be organ failure, but it had respiratory trouble and i thought it might be because of the disseminated nature of the disease, i mean systemic affections..
11 March at 20:28
Swarupmay Majumdar
thats the possibolity no 1, but it was an eye opener case
12 March at 11:39 ·
SC Pythosis form is really rare and respiratory form is really rare too :)
ReplyDeleteso here you are talking about two rare things that occur at once, not making since for me.
Purulent ocular discharge, this is abnormal, popliteal LN enlargement is not normal, responding to Itraconazole give rise to 3 things:
1) Fungal, which I cant see the ulceration on the limb, also respiratory form is rare and cutaneous form is rare and it is almost impossible for 2 rare conditions to occur at the same time.also it doesn't explain the other clinical signs.
2) Cancer some cancers respond to Itraconazole as it has anti-angiogenisis effect but i think the effect occur so soon.
3) The Edema disappeared by chance while other clinical signs were developing.
4)It was pythosis and another thing but you used ABiotic I think.
Still a huge Question any Idea's
Why ocular discharge occur, Anemia? and DEATH!!!!!
Thank you a lot for the posting of comments
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