Monday, March 29, 2010

thyroid values in dogs and why they dont help us in clinical diagnosis

Saurabh Saxena hi .pls update me on normal values of total T3,T4 and TSH in dogs?thanks

20 February at 18:46 · · · Report
Swarupmay Majumdar
Swarupmay Majumdar
canine normal T4=20-52nmol/L or 15-40ng/ml
T3=1.2-3.1nmol/L or 0.8-2ng/ml
t4 is more reliable than t3.T3 is usually normal in even Hypothyrd dogs but T4 usually below normal.Actually to tell the truth,Free T4 is best indiactive ,its just 1/10 of t4.
method of measurement: equilibrium dialysis method is superior,if not done in Equilibrium dialysis,... See moreneeds corrections.
all human lab methods are inaccurate for veterinary purose, so better to treat hypothyroidism based on clinincal signs than wait for inaccurate lab reports.
20 February at 19:13 ·
Darsha Mapatuna
Darsha Mapatuna
T4 20-60 nmol/L and TSH < 0.4ng/ml, analysis of T3 is of little diagnostic value in the diagnosis of hypothyroidism
20 February at 19:36 · Report
Cyril Roy
Cyril Roy
The values seem to be similar to that of horses (T4=20, T3=1). What i remember is that T3 is produced in the pheripheral systems like the muscles particularly in horses( I do not know about dogs though). So in horses T4 could be potentially more useful. But i agree with Swarupmay that normally lab tests for these conditions are least useful because these values has not been validated properly for each disease condition. The lab results can be just guidelines...
21 February at 00:50 · Report
Joseph Cyrus
Joseph Cyrus
JUst to make a point the reference should come from the veterinary lab. Please note t3, t4 and tsh are species specific and the only canine associated lab is the metropolis group in mumbai who do it!
28 February at 09:55 · Report
Swarupmay Majumdar
Swarupmay Majumdar
great one, from dr joseph
28 February at 11:32 ·

1 comment:

  1. T4 by ED is the best method for diagnosis. In cases when this is also wnl and the patient clinically looks like hypothyroid, then do the full panel, including the antibody also. Always keep sick euthyroid in mind.

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